Product Info Summary
SKU: | A04491 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, WB |
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Product info
Product Name
Anti-Leukocyte elastase inhibitor SERPINB1 Antibody
SKU/Catalog Number
A04491
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Leukocyte elastase inhibitor SERPINB1 Antibody catalog # A04491. Tested in WB,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Leukocyte elastase inhibitor SERPINB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04491)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SRp55
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04491 is reactive to SERPINB1 in Human, Mouse, Rat
Applications
A04491 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
42.742kDa
Background of SERPINB1
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Yeh E.T.H., Gene 248:1-14(2000).
Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Wiemann S., Genome Res. 11:422-435(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunofluorescent staining data of SERPINB1 using Anti-Leukocyte elastase inhibitor SERPINB1 Antibody (A04491).
Immunofluorescence analysis of Hela cellsClick image to see more details
Figure 1. Western blotting validation for Anti-Leukocyte elastase inhibitor SERPINB1 Antibody A04491
WesternBlot (WB) analysis of SERPINB1 polyclonal antibodyElectrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For SERPINB1 (Source: Uniprot.org, NCBI)
Gene Name
SERPINB1
Full Name
Leukocyte elastase inhibitor
Weight
42.742kDa
Superfamily
serpin family
Alternative Names
EILEI; ELANH2MNEI; elastase; leukocyte elastase inhibitor; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2; PI-2; PI2M/NEI; protease inhibitor 2 (elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; Serpin B1; serpin peptidase inhibitor, clade B (ovalbumin), member 1 SERPINB1 EI, ELANH2, HEL-S-27, HEL57, LEI, M/NEI, MNEI, PI-2, PI2 serpin family B member 1 leukocyte elastase inhibitor|epididymis luminal protein 57|epididymis secretory protein Li 27|peptidase inhibitor 2|protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1|serpin peptidase inhibitor, clade B (ovalbumin), member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SERPINB1, check out the SERPINB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SERPINB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Leukocyte elastase inhibitor SERPINB1 Antibody (A04491)
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No publications found for A04491
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Customer Reviews
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